Vibrio species have become a major source of concern for shrimp culture because of their close association with low survival rates in hatcheries or growout ponds. The present study was carried out to investigate in vitro antivibrio activity of marine sponge Callyspongia diffusa sp. The sponge extract was tested against four shrimp bacterial pathogens they are V.harveyi [NL] V.harveyi [L], V.parahaemolyticus, V.cholerae. A maximum zone of inhibition of sponge extract against test organisms V.harveyi [NL] 8 ± 0.1 mm in chloroform: methanol extract and 4± 1 mm in water extract followed by V.parahaemolyticus 6± 0.1 mm in choloroform: methanol extract and 3 ± 1 mm in water extract followed by V.cholerae 5± 0.1 mm in choloroform: methanol extract and 2 ± 1 mm in water extract .
Callyspongia diffusa sp, Vibrio cholerae, Vibrio harveyi, Vibrio parahaemolyticus.
