Objective: The clinical presentation of leukemia can vary widely in symptoms and signs, with different frequency in AML and ALL, whose prompt diagnosis and treatment is important for better survival. In current study we aimed to study spectrum of clinical presentations, age and sex factors, laboratory findings duration of symptoms in AML & ALL in pediatric patients of Rajendra Institute of Medical College, Ranchi.
Methodology: A retrospective documentary analysis of various clinical presentations of acute leukemias in childhood was conducted.
Result: Out of 2480 patients admitted during the study duration of 6 months, 26 patients were diagnosed as acute leukemia on the basis of 102 bone marrow studies with male to female ratio of 1.17:1. 30.8% cases were AML, 50% of cases were ALL while 19.2% cases of acute leukemia were unspecified.
Conclusion: The common symptoms in acute leukemia were weakness, fever, anorexia, pallor, localized swelling, weight loss, cough, arthralgia and pain abdomen. The commonest were weakness, fever, anorexia and pallor. Anemia, lymphadenopathy and organomegaly was more common in ALL as compared with AML.
Acute leukemia, ALL, AML, Clinical presentations, pediatric age
