SIDE EFFECTS OF LOCAL CORTICOSTEROID THERAPY

Author: 
E. Saiba, K. Ekemiri, J. Tuyishime and D. Achugwo.
Country: 
Rwanda
Abstract: 

Aim: The purpose of this research study was to find out the side effects of local corticosteroids (maxidrol and chibrocadron eye drops) among patients with allergic conjunctivitis at KUTH.
Objectives: The objectives of the study involved were; to determine the prevalence of allergic conjunctivitis at KUTH, to assess allergic conjunctivitis rate and associated subject’s occupation, to determine side effects of maxidrol and chibrocadron eye drops on patients with allergic conjunctivitis and finally to suggest the possible recommendations from the study
Results: The study revealed that the prevalence of allergic conjunctivitis in KUTH from 1 Received: J a n u a r y , 1 5  2 0 1 7 | Accepted: F e b r u a r y , 1 2  2 0 1 7 | Published Online: Ma r c h , 2 8  2 0 1 7 This is an Open Access article distributed under the terms of the Creative Commons Attribution License st July up to 31 December was 30.5%. Then, the disease affected all age groups even if the majority were between 21 and 25 years old. It has also affected both genders with predominance of female(55%) and it was more prevalent in educated people where students have had a significant percentage of allergic conjunctivitis about 55.6 % compared to the rest of the population. Furthermore, there was an increased in IOP less than 6 mmHg elevation among 139 patients (86.9%)  and IOP has increased more than 6-15 mmHg elevation among 21 patients (8.8%) who have had steroids induced cataract. Fortunately, there was no secondary ocular infection due to maxidrol or chibrocadron eye drops administration.
Conclusion: The study has revealed that both sexes were affected with predominance of females and allergic conjunctivitis was more associated with daily occupation of the patients. In addition, the study has also shown that allergic conjunctivitis has different presenting symptoms like redness, itching, foreign body sensation, photophobia and tearing. Then, it can co exist w ith other allergic disease such as allergic rhinitis and asthma. Furthermore, it has been revealed that 13.1 % of patients have had steroids induced intraocular hypertension while 14 patients ( 8.8%) had cataract secondary to long term use of Maxidrol and chibrocadron eye drops. Fortunately, there were no secondary ocular infections due to corticosteroids.

 

KeyWords: 

steroids induced intraocular pressure

Volume & Issue: 
Vol. 3, Issue 03
Pages: 
608-615
Download PDF: