Eclipta alba L. is commonly known as false daisy belonging to the Asteraceae family. The present study was designed to study the phytochemical composition and antimicrobial potential of ethanol and methanolic leaf extracts of Eclipta alba L. Phytochemical analysis was done using standard phytochemical methods. The crude leaf extracts of the plant were tested against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC BAA1705 and Pseudomonas aeruginosa ATCC 27853 by agar-well diffusion method. Ethanol and methanol leaf extract revealed the presence of carbohydrates, reducing sugars, alkaloids, fixed oil, saponins and phenolic compounds. The methanolic leaf extract showed the highest zone of inhibition compared with ethanolic leaf extract against all the tested bacterial pathogens. The results of the present study conclude that the studied plant possesses broad spectrum antibacterial properties.